Psilocybin & Magic Mushroom Guides
From preparation to integration, learn how to approach psilocybin safely and with intention.
Psilocybin Therapy
What it is, how it works, the 3-phase protocol, legal status, costs, and how to find a licensed facilitator.
Psilocybin for Depression
Clinical evidence: MADRS and remission by trial, DMN mechanism, psilocybin vs SSRIs. Strain picks on Best for Depression.
Psilocybin for Anxiety
What the research shows: Grob & Griffiths (existential/death anxiety), social anxiety data, amygdala & fear extinction. Strain picks: Best for Anxiety.
Psilocybin for Alcoholism
NYU/JHU RCT results, 83% reduction in heavy drinking days, 48% abstinence at 32 weeks. Protocol, access, and safety.
Psilocybin for Addiction
Evidence across nicotine, alcohol, opioids, and cocaine — Johns Hopkins 80% nicotine abstinence, mechanisms, and access.
Psilocybin for PTSD
Fear extinction mechanisms, Phase I/II trial data, Australia TGA 2023 prescription pathway, and how to access supervised treatment.
Microdosing
Protocols, dosage, benefits, safety, and the latest research. The complete 2026 guide.
Psilocybin vs SSRIs
Head-to-head clinical comparison of psilocybin and SSRIs — mechanism, remission rates, side effects, and who each treatment suits.
Psilocybin vs Ketamine
Clinical models, duration, access, and who each modality suits — ketamine clinics today vs psilocybin programs in Oregon and Colorado.
Oregon vs Colorado Psilocybin Therapy
Legal access decision guide: service centers, healing centers, facilitator rules, cost, travel, and who each state suits.
Psilocybin vs MDMA vs Ketamine
Therapy-use comparison by condition fit, evidence, mechanism, legal access, cost, and screening risks.
Microdosing on SSRIs
5-HT2A blunting, drug-by-drug SSRI interaction profiles, observational survey findings, and medically supervised transition guidance.
Psilocybin Drug Interactions
Medication and substance interaction hub covering contraindications, blunting, rescue agents, cannabis, alcohol, and tapering context.
Psilocybin and MAOIs
Why MAOIs can intensify psilocybin, which medications count, washout caveats, and why ayahuasca is not a casual safety analogy.
Psilocybin and Benzodiazepines
Benzos as rescue medication, chronic-use blunting, sedation risks, and why abrupt tapering before a session is unsafe.
Psilocybin and ADHD Medications
Adderall, Vyvanse, Ritalin, Concerta, atomoxetine, and what supervised protocols consider before dosing day.
Safe Trip
Set and setting, dosage safety, and how to reduce risk for a positive experience.
Trip Preparation
What to do in the days and hours before a journey: diet, mindset, and environment.
Trip Sitter
How to support someone on a journey — and when to sit for others.
Psychedelic Integration Workbook
A structured guide to process, understand, and apply psychedelic insights — domains, journal prompts, and support.
Ceremony Etiquette
Respectful behavior in group and ceremonial settings with sacrament.
How to Store
Keep your mushrooms potent, safe, and fresh with proper storage methods.
How to Grow
Basics of cultivating psilocybin mushrooms at home, legally and safely.