Fadiman Protocol
A microdosing schedule: one day on, two days off, then repeat. Named after researcher James Fadiman.
Full Explanation
The Fadiman Protocol is one of the best-known microdosing schedules. Developed by psychologist and researcher James Fadiman, it involves taking a sub-perceptual dose of psilocybin (typically 0.1–0.3g dried mushrooms) on Day 1, then taking Days 2 and 3 off, and repeating the cycle.
Why This Schedule
The two rest days allow you to notice any subtle effects and avoid building tolerance. Many microdosers use the "off" days to compare mood, focus, and creativity. The protocol is simple and well-suited to beginners.
Typical Use
People often follow the protocol for 4–8 weeks, then take a break of 2–4 weeks before resuming. Fadiman and others recommend journaling to track effects. The protocol is psilocybin-only (no Lion's Mane or niacin stack), unlike the Stamets Stack.
Why It Matters
The Fadiman Protocol is referenced in microdosing guides, dosage pages, and FAQs. Having a glossary entry helps readers who see "Fadiman" or "every 3 days" understand the schedule and how it compares to other protocols.
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Explore More Terms
Psilocybin
A naturally occurring psychedelic compound found in certain mushrooms that produces altered states of consciousness.
Psilocin
The pharmacologically active compound that psilocybin converts to in the body, responsible for psychedelic effects.
Ego Death
A temporary dissolution of the sense of self during a psychedelic experience, often described as profound and transformative.
Set and Setting
The combination of mindset (set) and environment (setting) that shapes a psychedelic experience.
Microdosing
Taking sub-perceptual doses of psilocybin on a regular schedule for subtle cognitive and emotional benefits.
Mycelium
The vegetative part of a fungus, consisting of a network of fine white filaments that eventually produces mushrooms.