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Psilocybin legal status in Colorado: laws, decrim & 2026 update

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Current psilocybin laws and regulations in Colorado

Current Legal Status

Colorado became the second U.S. state to legalize psilocybin when voters passed Proposition 122 (Natural Medicine Health Act) in November 2022. The law decriminalizes personal use and possession of psilocybin, DMT, ibogaine, and mescaline (excluding peyote) for adults 21 and older. It also establishes a regulated system for licensed healing centers to provide psilocybin services, with the first centers expected to open in 2024-2025. Denver had previously decriminalized psilocybin in 2019.

Timeline of Key Events

May 2019

Denver Decriminalizes

Denver becomes the first U.S. city to decriminalize psilocybin mushrooms.

November 2022

Proposition 122 Passes

Colorado voters approve statewide legalization of natural psychedelics.

January 2023

Personal Use Legal

Personal use and possession of psilocybin becomes legal for adults 21+.

September 2024

Healing Centers Begin

Colorado begins licensing psilocybin healing centers.

2025

DMT & Mescaline Added

Regulated access to DMT and mescaline expected to begin.

Psychedelic Churches in Colorado

Sacred Pillars Church

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Brands Available in Colorado

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Legal Disclaimer

While Colorado has legalized personal use and is developing a regulated healing center system, psilocybin remains illegal under federal law. Licensed healing centers are not yet operational as of early 2024. This information is for educational purposes only and does not constitute legal advice.