Your Trusted Guide to Psilocybin
& Magic Mushrooms
Evidence-based guides, harm-reduction tools, and a verified directory of psychedelic churches — all free.
Essential Guides
View all guides →Psilocybin Therapy
The three-phase protocol, what the trials show, and how legal access works in Oregon and Colorado.
Read guide →Microdosing Guide
Schedules, dose ranges, and what published studies do (and do not) support for microdosing.
Read guide →Safe Trip Guide
Set and setting, prep, navigating hard moments, and integration after a session.
Read guide →Psilocybin for Mental Health
View all conditions →Depression
Trial outcomes, who studies enroll, and how supervised models differ from casual use.
Read guide →Anxiety
Evidence in palliative and other settings, plus prep and safety considerations.
Read guide →PTSD
How trials structure sessions and how psilocybin is discussed alongside other PTSD care.
Read guide →Addiction
Research across substances and what "integration" means after a dosing session.
Read guide →Alcoholism
Key RCT results on drinking outcomes and how facilitated sessions are designed.
Read guide →Psilocybin vs SSRIs
Head-to-head trial takeaways: speed, side effects, and who each path may suit.
Read guide →Common Psilocybin Species
Dosage guide →Psilocybe cubensis
Well-StudiedThe species behind most cultivars and many clinical trials. Effects are better documented than for rarer species.
Psilocybe semilanceata
Some DataSmall and potent; common in temperate regions. Less trial data than P. cubensis.
Psilocybe azurescens
Limited DataVery potent; Pacific Northwest native. Treat potency and set/setting with extra care.
Latest Research & News
Single Psilocybin Dose Changes Brain Structure for a Month, Study Finds
A 2026 Nature Communications study in psychedelic-naïve adults found measurable brain-network and white-matter changes lasting at least a month after a singl...
5 Psychedelic Therapy Trends Shaping 2026
From COMP360's Phase 3 milestone to Colorado's rapid scale-up and MDMA's FDA resubmission, these are the five psychedelic therapy developments worth tracking...
Psilocybin Therapy Cost in 2026: What You'll Actually Pay
Legal psilocybin therapy in Oregon or Colorado costs $1,500–$3,500 per complete experience. Retreats abroad run $3,000–$8,000+. Here's exactly what drives co...